Questions? Comments? Please contact Dr. Phillip McClean or Christina Johnson.

OVERVIEW
Flythrough Tour
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MOLECULAR PROCESSES
Transcription
Regulated Transcription
mRNA Processing
mRNA Splicing
Translation
Lac Operon
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CELLULAR PROCESSES
Protein Trafficking
Protein Modification
Protein Recycling
Insulin Signaling
Constitutive Secretion
Regulated Secretion
Mitochondrial Protein Transport
Mitosis
Meiosis
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CELLULAR ENERGY CONVERSION
Atp Synthase (Gradients)
Electron Transport Chain
Photosynthesis (Light Reaction)
Photosystem II
Glycolysis (Overview)
Glycolysis (Reactions)
Citric Acid Cycle (Overview)
Citric Acid Cycle (Reactions)
Energy Consumption
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HOME > FLYTHROUGH > CLOSER LOOK > 1.) NUCLEUS > 2.) ER & GOLGI
Through the Virtual Cell --> 2.) ER & Golgi

Proteins are translated into the ER and then carried to the Golgi apparatus where they are packaged into vesicles and transported throughout the cell. Clicking on each of the thumbnail images will bring up a larger, labeled version of the described scene.

To see the Flash movie for the following sequence of images, click here.

After entering the cytoplasm, mRNA binds to a ribosomal sub-unit and serves as a template for translation--the process by which ribosomes, mRNA, and tRNA join together and build proteins out of specific amino acids.

Ribosomes can be found floating in the cytoplasm of the cell, or attached to the endoplasmic reticulum or nuclear membrane. Ribsomes attached to the ER insert the proteins they translate directly into the space inside the ER membrane.

Proteins from inside the ER can be packaged into cargo vesicles and transported along microtubules to the Golgi apparatus for further modification and distribution within the cell.

Inside the Golgi, some proteins are modified with specific molecular tags. These tags help to target the protein to its final destination.

As the Golgi cisternae mature, they eventually join the Trans Golgi Network and break off into transport vesicles. These vesicles contain proteins destined for specific locations within the cell.

Hydrolase enzymes are tagged for delivery to organelles such as the endosome.

Other proteins like interleukins, are destined for delivery to the cell's plasma membrane where they will be secreted from the cell.

NEXT --> 3.) MITOCHONDRIA

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